This page is supervised by a specialist physician at IC Clinic Shinjuku, located a 3-minute walk from JR Shinjuku Station.
A Complete Guide to Wrinkle Treatments in Tokyo (Shinjuku)
What Causes Wrinkles and How Can You Address Them? 8 Treatments to Help Improve Wrinkles and Sagging
“I’m bothered by smile lines at the corners of my eyes.”
“I’ve started noticing more wrinkles and sagging on my face as I age.”
Do any of these concerns sound familiar?
Skincare alone—such as creams and serums—may not be sufficient to visibly improve wrinkles. For this reason, those who wish to address their wrinkles are encouraged to consider clinical treatment.
This page explains the causes of wrinkles, preventive measures, and available clinical treatments. We hope it will be a helpful resource for anyone concerned about wrinkles—please read on.
Why Do Wrinkles Form? Two Key Causes
The causes of wrinkles differ depending on where they develop. Wrinkles that form in the epidermis are caused by skin dryness, while wrinkles that form in the dermis are triggered by repeated facial movements.
Let’s take a closer look at these two main causes of wrinkles.
Epidermal Wrinkles | Temporary Lines Caused by Dryness
Fine lines around the eyes and mouth—commonly called “fine wrinkles”—are primarily caused by skin dryness. The epidermis refers to the outermost layer of the skin.
When the skin becomes dry, the stratum corneum tends to flake, allowing moisture to evaporate through the gaps, making wrinkles more likely to appear.
Fine lines can develop even in younger individuals, but because younger skin retains its elasticity, these lines tend to be temporary. As the skin ages and loses elasticity with time, fine lines that develop become more difficult to reverse.
Dermal Wrinkles | Lines Formed by Repeated Facial Expressions
Wrinkles arising from changes in dermal cells are known as “dermal wrinkles.”
The dermis refers to the layer of skin beneath the epidermis. Dermal wrinkles develop as a result of repeated facial movements over time.
The underlying cause of dermal wrinkles is the deterioration and reduction of collagen, which provides firmness to the skin, and elastin, which supports skin elasticity.
UV damage can decrease the number of fibroblasts—the cells responsible for producing collagen and elastin—or impair their ability to produce these proteins altogether. As a result, collagen and elastin levels decline, causing the skin to lose its firmness.
When facial expressions are repeatedly made on skin that has already lost its firmness, wrinkles that form tend to become difficult to smooth out.
Dermal wrinkles can be divided into fine lines that run perpendicular to the facial muscles, and deeper wrinkles around the mouth and along the facial contour that develop with age.
How to Prevent Wrinkles and Sagging: The Importance of Sun Protection
Sun protection is essential for preventing wrinkles and sagging.
Among the various types of wrinkles, the more serious dermal wrinkles develop as UV exposure reduces collagen, elastin, and other proteins in the body. UV rays also cause the dryness that leads to epidermal wrinkles.
There are several types of UV radiation, but UVA—which penetrates deep into the skin—is particularly associated with wrinkle formation.
UVA that reaches deeper layers of the skin damages fibroblasts, the cells responsible for producing collagen, elastin, and similar substances. Skin that has lost its elasticity due to UVA exposure is at increased risk of developing wrinkles and sagging.
UVA also increases melanin, the substance responsible for pigmented spots, so sun protection is important for maintaining a youthful-looking complexion.
Because UVA is emitted in large quantities and penetrates deep into the skin, its impact on wrinkle formation is significant. It also passes through glass and reaches the skin, making year-round sun protection necessary.
Can Cosmetics Improve Wrinkles? Tips for Choosing Creams and Serums
There is a possibility that wrinkles may be improved through the use of cosmetics. However, the approach differs depending on whether the wrinkles are epidermal or dermal.
For epidermal wrinkles, diligent moisturizing to maintain skin texture and promote skin turnover may offer a path to improvement. Skin turnover refers to the cycle in which skin cells are regularly renewed.
Improving the skin’s turnover cycle may help make wrinkles less noticeable. By thoroughly moisturizing, the stratum corneum is kept from drying out, which can help normalize the pace of skin turnover.
For dermal wrinkles, using creams and serums that contain ingredients related to collagen and elastin is important. However, collagen molecules are large and do not readily absorb into the skin, so topical application alone may yield limited results.
It is necessary to increase collagen from within the skin by stimulating fibroblasts—the cells that produce collagen—as well as dermal stem cells, which give rise to fibroblasts.
Causes and Ways to Address Neck Wrinkles
Like the face, neck wrinkles are one of the signs that strongly suggest aging. However, the skin on the neck is thinner than on the face, has fewer sebaceous glands, and is therefore prone to dryness. Combined with the frequent movements of the neck in daily life, this area tends to be particularly susceptible to wrinkles. Neck care is often overlooked, but comprehensive care that extends to the neck is key to maintaining a youthful appearance.
Daily Habits to Help Prevent Neck Wrinkles
Everyday lifestyle habits have a significant impact on neck wrinkles. In modern life especially, the increasing use of smartphones and the prevalence of desk work tend to place added strain on the neck.
1. Improving posture:
* Text neck (straight neck): Looking down at a smartphone or tablet for extended periods keeps the neck skin in a constantly folded position, which is a major contributor to deeper wrinkle formation. Make a habit of consciously raising your device to eye level when using it, and take regular breaks to stretch the neck.
* Posture during desk work: When working at a computer for long periods, adjust the screen to eye level and make a conscious effort to sit with your back straight. Slouching or leaning forward not only strains the neck but can also lead to shoulder stiffness and headaches.
2. Reviewing pillow height:
* Bedding—especially pillow height—directly affects neck wrinkles. A pillow that is too high can bend the neck at an unnatural angle during sleep, contributing to deeper wrinkles. Conversely, a pillow that is too low may also strain the neck.
* Choosing a pillow of appropriate height that conforms to the natural S-curve of the neck and allows for easy repositioning during sleep is important. Consulting a bedding specialist to find a pillow that suits you is a worthwhile step.
3. Adjusting sleeping positions:
* Sleeping on your back is generally considered ideal. Sleeping on your side or face down places strain on the neck, promotes wrinkling, and makes the skin more susceptible to friction damage.
* Choosing a pillowcase made of a smooth, low-friction material such as silk can also help reduce stress on the skin.
4. Sun protection:
* Like the face, the neck is exposed to UV rays year-round. V-neck tops in particular can leave the neck area more exposed.
* Make it a habit to apply sunscreen to the neck throughout the year. In summer, wearing a UV-protective stole or scarf can be helpful as well.
Skincare Methods That May Help With Neck Wrinkles
Combining everyday lifestyle adjustments with skincare focused specifically on the neck may help enhance the improvement of wrinkles.
1. Thorough moisturizing:
* Because the neck has fewer sebaceous glands and is prone to dryness, it requires even more careful moisturizing than the face.
* Make it a habit to apply toner, lotion, and cream to the neck just as you would to your face. If dryness is a concern, you may also want to consider a body cream with a higher oil content or a cream formulated specifically for the neck.
* Applying moisturizing products generously while the skin is warm and supple—such as after a bath or shower—may be more effective.
2. Using neck-specific creams and serums:
* There is a growing range of creams and serums formulated specifically for neck wrinkles and sagging, containing ingredients such as firming agents, hydrating ingredients, and tightening agents. Incorporating these targeted products into your routine may allow for more intensive care.
3. Proper massage techniques:
* The skin of the neck is delicate, so it is important to avoid strong friction and massage gently.
* Lymphatic massage: Using your fingertips, gently massage from the neck down toward the collarbone and décolletage to encourage lymphatic drainage. This may help remove waste products, improve circulation, and support skin metabolism.
* Upward massage: Using the full palm of your hand, gently lift the skin from the base of the neck toward the jaw. Performing this while applying cream—as if smoothing out the wrinkle grooves—may enhance the effect.
* Always apply a generous amount of cream or oil before massaging to reduce friction.
4. Stretching and exercise:
* Stretching to loosen the neck muscles and promote circulation may also be helpful. Incorporate gentle neck rolls and side-to-side tilts into your daily routine.
* Stretches targeting the neck and shoulders that help improve posture can also be beneficial.
Approaches to Improving Wrinkles
Elevating the quality of your daily skincare is extremely important when it comes to addressing wrinkles. Choosing the right products and using them correctly can make a noticeable difference to your skin. In addition, caring for your body from the inside and reviewing your daily lifestyle habits are also essential for preventing and improving wrinkles.
How to Choose and Use Anti-Wrinkle Creams
There are many anti-wrinkle creams on the market, and selecting the right product and using it correctly is key to noticing a difference.
How to choose:
1. Check for recognized quasi-drug active ingredients:
* Look for products containing active ingredients officially recognized by the Ministry of Health, Labour and Welfare as effective for improving wrinkles. Key examples include the following.
* Pure retinol: Promotes skin cell turnover and encourages the production of collagen and elastin, with potential to address deeper wrinkles.
* Niacinamide: A multifunctional ingredient that may support collagen production, improve the skin barrier, and inhibit melanin formation—making it potentially useful for wrinkles, skin brightening, and skin roughness.
* NEI-L1: (A Pola Orbis ingredient) Works to inhibit the enzymes that break down collagen and elastin in the dermis, potentially enhancing skin elasticity.
* Products containing these ingredients are classified as quasi-drugs (医薬部外品) and will state claims such as “improves wrinkles” on their packaging.
2. Prioritize moisturizing ingredients:
* Dryness is a concern for all types of wrinkles. Check that the product contains sufficient amounts of high-hydration ingredients such as hyaluronic acid, ceramide, collagen, and glycerin. Keeping the skin well hydrated may help fine lines appear less visible and can support overall skin health.
3. Choose a texture suited to your skin type and concerns:
* Since a cream is used every day, selecting one that feels comfortable—not overly greasy—and absorbs well is key to maintaining consistent use. Those with dry skin may prefer a richer formula, while those with combination skin may find a lighter texture more suitable.
4. Select an affordable price range you can sustain:
* Consistent use over time is more important than immediate results for wrinkle care. Choose a product within a price range that you can realistically maintain. In some cases, using a moderately priced product every day may be more beneficial than using an expensive one only occasionally.
How to use:
1. Timing of application: As a general guide, apply after cleansing, toning with lotion, and using serums, before your moisturizer or cream. The recommended order may vary by product, so always check the instructions.
2. Amount: Each product specifies an appropriate amount to use. Using too little may reduce effectiveness, while using too much could place unnecessary stress on the skin.
3. Application method:
* Apply gently with your fingertips: For delicate areas such as around the eyes and mouth where the skin is thin, use the pads of a weaker finger—such as the ring finger—and apply with a gentle touch.
* Work along the wrinkles: Lightly smooth the product along the wrinkle grooves, pressing it gently into the skin as if encouraging absorption.
* Avoid rubbing: Strong friction can stress the skin and may contribute to further wrinkle formation, so be careful never to rub the product in.
* Layering: For areas of particular concern, applying a small amount in layers—”intensive care”—may also be helpful.
4. Morning and evening care: Using the product twice daily, morning and evening, may help you notice results more readily. When applying in the morning, be aware that some ingredients can increase sensitivity to UV exposure, so always apply sunscreen over the top.
The Effects of Retinol and Vitamin C Derivatives
Retinol and vitamin C derivatives are among the most notable ingredients for addressing wrinkles. They work through different mechanisms to support skin improvement.
Retinol (Vitamin A):
* Effects on the skin:
* Promotes skin turnover: Helps normalize the cycle in which old skin cells are shed and new ones are generated, which may smooth the skin’s surface and reduce the appearance of fine lines.
* Supports collagen and elastin production: Acts on fibroblasts in the dermis to encourage the production of collagen and elastin, which support skin firmness and elasticity—potentially leading to improvement of deeper wrinkles from within the skin.
* Supports hyaluronic acid production: May also promote the production of hyaluronic acid, which helps maintain the skin’s moisture-retaining capacity.
* Types and characteristics:
* Pure retinol: Associated with stronger effects, but also more prone to causing skin reactions (known as “retinization”: redness, peeling, dryness, etc.). It is advisable to start with a small amount and gradually allow the skin to adjust.
* Retinol derivatives: Such as retinyl palmitate and retinyl acetate. These tend to be gentler on the skin and are more suitable for beginners. Effects are more gradual than pure retinol, but stability is generally better.
* Points to note when using:
* Sensitive to light: Retinol can become unstable when exposed to light, so nighttime use is recommended.
* Sun protection is essential: The skin may become more sensitive to UV exposure while using retinol, so a sunscreen with a high SPF and PA rating must be applied during the day.
* Watch for irritation: When using for the first time, perform a patch test on the inner arm and start with a small amount, monitoring how your skin responds. It is generally advisable to avoid use during pregnancy or while breastfeeding.
Vitamin C Derivatives:
* Effects on the skin:
* Potent antioxidant action: Helps neutralize free radicals generated by UV exposure and stress, protecting skin cells from damage. This may help prevent the breakdown of collagen and elastin and support the management of UV-related skin aging.
* Supports collagen production: An essential component for collagen synthesis, which supports skin firmness and elasticity—potentially contributing to wrinkle improvement from within.
* Inhibits melanin production: Also has a role in suppressing the production of melanin responsible for pigmented spots, contributing to an overall improvement in skin tone.
* Controls sebum secretion: May also help regulate excess sebum, with potential benefits for visible pores and acne-prone skin.
* Types and characteristics:
* A variety of forms are available—including magnesium ascorbyl phosphate, sodium ascorbyl phosphate (water-soluble), ethyl ascorbic acid (both water- and oil-soluble), and APPS (amphiphilic)—each with different levels of penetration, stability, and potential for irritation.
* Points to note when using:
* Many formulations offer relatively good stability and can be used both morning and evening, but some individuals may experience mild irritation, so monitor how your skin responds.
* If dryness is a concern, look for products that combine vitamin C derivatives with moisturizing ingredients.
The Role of Hyaluronic Acid and Collagen
Hyaluronic acid and collagen play a very important role in maintaining skin hydration and elasticity. When these components are depleted, the skin becomes dry, loses its elasticity, and wrinkles and sagging become more noticeable.
Hyaluronic acid:
* Its role in the skin:
* Hyaluronic acid is a type of mucopolysaccharide with an exceptionally high water-retaining capacity—said to be capable of holding up to 6 liters of water per gram.
* It is found abundantly in the dermis, where it fills the spaces between cells to store moisture in the skin, giving it a cushion-like elasticity and suppleness.
* Effects on wrinkles:
* It may be particularly effective at reducing the appearance of fine lines caused by moisture loss on the skin’s surface. When the skin is well hydrated, its texture appears more refined and fine wrinkles appear plumped up.
* By increasing the overall moisture content of the skin, it also supports the skin’s barrier function, helping to protect against external stressors.
* How to use:
* Topical application: Applying hyaluronic acid–containing toners, serums, and creams provides moisture to the outer layers of the skin to help prevent dryness. Using products that combine hyaluronic acid molecules of different sizes is thought to allow penetration to deeper layers.
* Oral supplementation: It has been reported that orally consumed hyaluronic acid may be partially absorbed by the body and may contribute to improvements in skin moisture levels.
Collagen:
* Its role in the skin:
* Collagen is the principal protein in the dermis, accounting for approximately 70% of its composition. It forms a fibrous structure that provides the skin’s foundation.
* Arranged in a mesh-like network together with elastin—a rubber-like elastic protein—collagen plays a key role in maintaining the skin’s resilience and firmness.
* Effects on wrinkles:
* When collagen is reduced or its structure deteriorates due to aging or UV damage, the skin loses its elasticity, which can directly contribute to the development of wrinkles and sagging.
* Supplementing collagen is expected to support skin elasticity and help smooth wrinkles by lifting the skin from within.
* How to use:
* Topical application: Hydrolyzed collagen and other forms with reduced molecular size are incorporated into cosmetics to help with moisturizing and supporting a firmer feel.
* Dietary intake: A balanced diet that includes animal proteins (meat, fish, eggs) and collagen-rich foods (chicken skin, fish skin, shark fin, etc.) is beneficial. To efficiently produce collagen in the body, it is also important to consume sufficient vitamin C.
* Supplementation: Low-molecular-weight collagen peptide supplements may also contribute to improvements in skin elasticity and hydration.
Foods and Nutrients That May Help With Wrinkles
Skin health is closely linked to daily dietary habits. To help prevent and address wrinkles, it is important to actively consume nutrients that support the skin from within. Aim for a balanced diet to strengthen the foundation of your skin.
Astaxanthin (Found in Red-Colored Foods)
Astaxanthin is the reddish pigment found in shrimp, crab, and salmon, and is a type of carotenoid with a particularly potent antioxidant effect. It is said to have an antioxidant capacity far greater than that of vitamin E, and is expected to help protect skin cells from free radicals generated by UV exposure, potentially helping to manage the development of UV-related skin aging and wrinkles.
* Foods that contain it: Salmon, salmon roe, shrimp, crab, sea bream, supplements containing astaxanthin, and more.
* Tips for consumption: Absorption may be enhanced when consumed with fat, so grilled salmon or dishes such as ajillo are recommended.
Vitamins A, C, and E (The “ACE” Vitamins)
Vitamins A, C, and E each have distinct functions and work together to help maintain skin health and support wrinkle improvement.
* Vitamin A (β-carotene):
* Function: Promotes skin cell turnover (renewal), helping to shed old skin cells and support the generation of new ones. This may help refine skin texture and reduce the appearance of fine lines. It also helps maintain the health of skin and mucous membranes. Consuming it as β-carotene, which is converted to vitamin A in the body as needed, is considered a safe approach.
* Foods that contain it: Dark-colored vegetables such as carrots, spinach, pumpkin, and broccoli; eel; liver; and more.
* Vitamin C:
* Function: Has a potent antioxidant effect, helping to neutralize free radicals generated by UV exposure and other sources. It is also an essential nutrient for collagen synthesis, playing an important role in maintaining skin firmness and elasticity. It additionally helps suppress melanin production, making it potentially useful for both pigmented spots and wrinkles.
* Foods that contain it: Citrus fruits (lemon, orange), strawberries, kiwifruit, broccoli, bell peppers, potatoes, and more.
* Vitamin E:
* Function: Sometimes called the “anti-aging vitamin,” it supports circulation and has antioxidant properties. By protecting cell membranes from oxidation, it may help slow skin aging and support cellular metabolism—contributing to improved skin barrier function and a more supple, hydrated complexion.
* Foods that contain it: Nuts (almonds, peanuts), avocado, vegetable oils (sunflower oil, rapeseed oil), eel, and more.
Protein
Collagen and elastin—the key structural components of the skin—are made from protein. Consuming sufficient high-quality protein is therefore essential for strengthening the skin’s foundation and helping to prevent wrinkle formation.
* Function: Collagen, elastin, and even the enzymes and cells needed for skin turnover are all made from protein. A deficiency can cause the skin to lose firmness and elasticity, making it more prone to wrinkles.
* Foods that contain it: Meat (chicken breast, tenderloin, lean cuts), fish and seafood (white fish, oily fish), eggs, soy-based products (tofu, natto, soy milk), dairy products (milk, yogurt, cheese), and more.
* Tips for consumption: It is advisable to obtain protein from a variety of sources without relying on one type, and to choose foods with a high amino acid score.
Key Nutrients and Food Examples for Wrinkle Care
| Nutrient | Key Functions | Foods That Contain It |
| Astaxanthin | Potent antioxidant action, UV damage protection | Salmon, salmon roe, shrimp, crab |
| Vitamin A | Promotes skin turnover, maintains skin and mucous membrane health | Carrots, spinach, pumpkin, eel |
| Vitamin C | Supports collagen production, antioxidant action, inhibits melanin | Citrus fruits, strawberries, kiwifruit, broccoli, bell peppers |
| Vitamin E | Antioxidant action, supports circulation, activates skin metabolism | Nuts, avocado, vegetable oils |
| Protein | Building block for collagen and elastin, strengthens skin foundation | Meat, fish, eggs, soy products, dairy products |
| Polyphenols | Antioxidant action, cell protection | Blueberries, green tea, red wine, cacao, coffee |
| Ceramide | Strengthens skin barrier function, retains moisture | Konjac, rice, wheat, milk, yogurt (small amounts from food sources) |
Wrinkle Prevention Beyond Skincare
Beyond skincare products, small adjustments and mindful habits in everyday life can help prevent wrinkles and keep them from worsening. However, it is important to avoid misinformation and potentially harmful methods that could place unnecessary stress on the skin.
Using a Clothes Steamer (Important Cautions for the Skin)
Clothes steamers are designed to remove wrinkles from fabric, and you should never apply one directly to the skin. The high-temperature steam poses a serious risk of burns and can dry out the skin, potentially causing damage rather than benefit.
That said, from an indirect perspective, indoor humidity management is important since skin dryness is a major contributing factor to wrinkles. Rather than applying a clothes steamer directly to the skin, using one on clothing in a clean environment may have a temporary incidental effect on indoor dryness, though a humidifier is recommended for proper humidity control.
Spray Bottles and Hair Dryers (Risks to the Skin)
The practice of misting the face with a spray bottle and then drying it with a hair dryer is extremely dangerous as a wrinkle-prevention method and should never be attempted.
Even if moisture is applied via a spray bottle, the air from the hair dryer causes rapid evaporation that strips the skin of its natural moisture along with the added water. This can significantly worsen skin dryness, weaken the barrier function, and ultimately contribute to deeper wrinkles.
The foundation of wrinkle prevention is “moisturizing” and “preventing moisture loss.” When adding moisture to the skin, use a lotion or mist containing hydrating ingredients, and promptly follow up with a milky lotion or cream to seal in moisture and lock it inside the skin.
How to Use a Hot Towel
When used correctly, a hot towel may indirectly support wrinkle care. The warmth may help promote circulation and support skin metabolism. It can also help open the pores, potentially improving the absorption of skincare products applied afterward.
* How to use:
1. Wet a clean towel with water and wring it out lightly.
2. Warm it in the microwave for approximately 30 seconds to 1 minute (check carefully to ensure it is not too hot—be cautious of burns).
3. Place the warm towel on your face or neck for a few minutes and relax.
4. After using the hot towel, apply toner, serum, and cream promptly before moisture evaporates from the skin.
* Note: If the towel is too hot, it may stress the skin, so please pay close attention to the temperature. Also, avoid leaving it on for too long.
Hair Straighteners (Effects on the Skin)
Hair straighteners are designed for hair styling, and you should never apply one directly to the skin. The high-temperature plates can cause severe burns and damage to the skin, potentially leaving lasting marks that cannot be reversed—let alone improving wrinkles.
It is also important to take care when styling your hair that the hot air or heated plates do not come into contact with the skin around the face. Hair dryness can sometimes be linked to skin dryness as well. Maintaining healthy hair can have an indirect positive effect on skin health, so when using a hair straightener, choose an appropriate heat setting and use a heat protectant—giving consideration to the skin on your face as well as your hair and scalp.
Conditions That Are Sometimes Confused With Wrinkles
While people often identify their skin concerns as “wrinkles,” some conditions that appear similar have different underlying causes and characteristics. In particular, “nasolabial folds” and “sagging” are frequently confused with wrinkles, but understanding the distinctions between them can lead to more targeted and effective approaches.
The Difference Between Wrinkles and Nasolabial Folds
Nasolabial folds are the lines that run from the sides of the nose down toward the corners of the mouth in a shape resembling the katakana character “ハ,” and they are a common facial concern for many people. Although they are often treated as “wrinkles,” strictly speaking they are more accurately described as “grooves” that involve elements of both wrinkles and sagging.
* What wrinkles are:
* Fine, shallow lines on the skin’s surface or folds in the skin. They develop primarily when the skin loses its elasticity due to dryness, UV damage, and repeated facial expressions.
* Examples: fine lines at the corners of the eyes, vertical frown lines between the brows, horizontal lines on the forehead.
* What nasolabial folds are:
* The main causes are weakening of the facial muscles, an increase or descent of subcutaneous fat, and sagging resulting from a reduction in collagen and elastin in the dermis. The cheek skin droops downward, creating a “groove” as a result. Bone structure, dental alignment, and habitual facial expressions also play a role.
* As nasolabial folds deepen, they create shadows that make them more visible and contribute to a more aged appearance.
Why understanding the difference matters:
While wrinkles are primarily addressed through surface-level skincare (moisturizing, applying active ingredients), nasolabial folds are caused by sagging, and therefore require more fundamental approaches—such as facial muscle exercises, lifting-focused skincare, and aesthetic medicine (hyaluronic acid injections, thread lifts, HIFU, etc.). Understanding the root cause rather than treating them interchangeably allows you to choose the right approach.
The Relationship Between Wrinkles and Sagging
Sagging refers to a condition in which the skin and underlying tissue gradually descend as the skin loses its firmness and elasticity due to aging, UV exposure, gravity, and lifestyle factors. Wrinkles and sagging are closely related and often appear together, which can make it difficult to identify which is the primary cause.
* What sagging is:
* The face is pulled downward overall, resulting in a loosening of the facial contour, drooping of the cheeks, and puffiness under the eyes (sagging-related dark circles).
* Key causes include a reduction or deterioration of collagen and elastin in the dermis, an increase or descent of subcutaneous fat, and weakening of the facial muscles.
* The relationship with wrinkles:
* Sagging leads to wrinkles: When sagging causes excess skin or skin folds to develop, deeply set wrinkles (such as nasolabial folds and marionette lines) can form. For example, when the cheeks sag, the added weight can make deep creases more likely to appear at the corners of the mouth.
* Wrinkles can accelerate sagging: If fine lines caused by dryness are left unaddressed, the skin’s barrier function may deteriorate, allowing damage to accumulate in the dermis. This can eventually lead to a loss of skin elasticity and contribute to sagging.
* Shared causes: Factors such as UV exposure and aging affect both wrinkles and sagging.
Approach to treatment:
Addressing sagging shares a great deal in common with wrinkle care, but in addition to treatments that support collagen and elastin production (such as retinol and vitamin C derivatives), more fundamental approaches are often helpful—including strengthening the facial muscles and aesthetic medicine procedures for lifting (HIFU, laser treatments, thread lifts, etc.). Incorporating comprehensive anti-aging care that addresses both wrinkles and sagging is important for maintaining a youthful complexion.
For a More Fundamental Approach to Wrinkle Improvement, Consider Consulting a Clinic
If you would like a more fundamental approach to improving wrinkles, visiting a clinic for treatment is one option worth considering beyond over-the-counter cosmetics. Most over-the-counter cosmetics can only penetrate as far as the epidermis—the outermost layer of the skin.
Because many of the cells involved in wrinkle improvement are located in the dermis, skincare products alone tend to offer limited results.
At a clinic, treatments and medical devices that can reach the dermis are available. If you are looking for ways to address wrinkles, we encourage you to consider professional treatment at a clinic.
8 Wrinkle Treatments Available at IC Clinic
The types and features of wrinkle treatments available at our clinic are as follows.
| Treatment | Description | Suitable For |
|---|---|---|
| Dermapen Microneedling | Creates micro-channels in the skin using fine needles | Those concerned about fine lines |
| ICON | Delivers specialized light energy to the skin | Those without active skin inflammation |
| Agnes | Delivers radiofrequency current via insulated micro-needles | Those who wish to wear makeup the day after treatment |
| Fractional Laser | Delivers fine laser beams to the skin | Those seeking to improve skin firmness and elasticity |
| HIFU | Uses ultrasound to address skin sagging | Those who would like to notice results relatively quickly |
| Botulinum Toxin Injections | Injected to reduce muscle contractions | Those wishing to address expression lines on the forehead or between the brows |
| Hyaluronic Acid Injections | Injected to add volume and hydration | Those seeking firmer, more supple skin |
| Thread Lift | Threads are inserted to lift and tighten the skin | Those seeking a higher degree of wrinkle improvement |
Below, we explain the features, potential benefits, possible side effects, and costs of each treatment.
1. Dermapen Microneedling
Dermapen Microneedling is a treatment that uses fine needles to create tiny channels in the skin, stimulating the skin’s natural renewal process. When the needles are inserted, fibroblasts are activated, encouraging the production of collagen and other substances that influence wrinkle formation.
Please note, however, that results do not appear immediately after treatment. Dermapen typically requires an average of around 5 sessions, with intervals of approximately 3 to 4 weeks between each.
For those concerned about cost, your first session of Dermapen at our clinic is available at a reduced introductory price.
For more details about Dermapen, please visit the following page.
2. ICON
ICON is a medical device that delivers a form of phototherapy called IPL (Intense Pulsed Light) therapy, using a specialized light to treat the skin.
By adjusting the light intensity, ICON can address a range of skin concerns beyond wrinkles. By delivering light to the dermis and stimulating fibroblasts, it encourages collagen production.
This can help build skin that is more resilient against UV exposure and dryness, with the potential to reduce superficial wrinkles. However, there are some limitations—for example, treatment is not suitable for pregnant individuals or those with active skin inflammation.
If you are unsure whether your skin condition is suitable for this treatment, please feel free to consult our clinic.
Please also note that approximately 5 to 6 sessions are typically needed for optimal results. The treatment fee for ICON at our clinic is “Full face 6 sessions / ¥110,000 (tax included: ¥121,000).”
For more information about ICON, please visit the following page.
3. Agnes
Agnes uses high-frequency insulated micro-needles to work directly on the dermis, making it effective even for skin concerns that are difficult to address with surface-level skincare alone.
For wrinkle treatment, Agnes is particularly well suited for addressing fine lines under the eyes. Because the skin under the eyes is thin, some treatments such as botulinum toxin injections may not reach this area effectively—but the insulated micro-needles used in Agnes allow treatment to reach the dermis.
Agnes delivers high-frequency current through the needles to stimulate the skin, encouraging the production of collagen and elastin. Because this process does not damage the epidermis, downtime is minimal, and it is generally possible to wear makeup from the day after treatment.
Side effects such as redness, swelling, or bruising may occasionally occur, but in most cases these resolve within one week. The treatment fee for Agnes at our clinic is “Full face 6 sessions / ¥324,000 (tax included: ¥356,400).”
For more information about Agnes, please visit the following page.
AGNES for Acne Removal and Under-Eye Care! Pricing, Effects, and 4 Clinical Case Examples
4. Fractional Laser
Fractional laser treatment involves delivering fine laser beams to create controlled thermal damage in the deeper layers of the skin, stimulating skin rejuvenation. As the skin repairs the laser-induced micro-injuries through cell division, collagen production is stimulated.
The treatment is available in two types: ablative, which uses higher energy output, and non-ablative, which uses lower output and involves shorter downtime.
In addition to improving wrinkles through skin regeneration, improvements in skin firmness and elasticity through collagen remodeling may also be expected.
Side effects such as pain, redness, and post-inflammatory hyperpigmentation may occur after treatment, but these typically improve over time. The treatment fee for fractional laser at our clinic is “Full face 6 sessions / ¥110,000 (tax included: ¥121,000).”
For more information about fractional laser treatment, please visit the following page.
What Is Fractional Laser? 3 Skincare Effects Including Improvement of Scars and Enlarged Pores
5. HIFU
HIFU (High-Intensity Focused Ultrasound) is a treatment that uses ultrasound energy to address skin sagging. Because the ultrasound can be directed to the SMAS (superficial musculoaponeurotic system)—the muscular foundation of the face—it can deliver a notable tightening effect.
In particular, the “Ultraformer III” used at our clinic is designed with a focus on delivering a noticeable tightening effect while minimizing discomfort.
While individual results may vary, some patients notice an improvement in their wrinkles relatively soon after treatment.
Redness or a warm sensation may be experienced after treatment, but these are typically temporary and tend to subside within about one week. The fee for HIFU at our clinic is “Full face 5 sessions / ¥135,000 (tax included: ¥148,500).”
For more information about HIFU, please visit the following page.
What Is HIFU? The “Ultraformer III” for Facial Sagging Improvement
6. Botulinum Toxin Injections
Botulinum toxin injections relax the muscles at the injection site to create a smoother appearance and can also help address wrinkles on the forehead and between the brows.
Muscle contraction is a contributing factor in many types of wrinkles. Botulinum toxin injections can reduce muscle contractions, which may help lessen the appearance of wrinkles.
Possible disadvantages include the risk of swelling, discomfort, or bruising, as well as the possibility of unnatural facial expressions.
Because the treatment works by reducing activity in facial muscles, an overly pronounced effect could make it more difficult to move the muscles as intended.
The fee for botulinum toxin injections at our clinic varies depending on the treatment area. For more information about botulinum toxin treatment, please visit the following page.
What Are Botulinum Toxin Injections? 5 Potential Aesthetic Benefits and Possible Side Effects
7. Hyaluronic Acid Injections
This treatment involves injecting hyaluronic acid—which has excellent moisturizing and water-retaining properties along with elasticity—into targeted areas.
When hyaluronic acid is injected into wrinkle grooves, the dermis lifts the overlying epidermis, adding volume to the skin overall. This can make wrinkles and nasolabial folds less noticeable, providing a visible improvement.
Hyaluronic acid is a substance naturally present in the body, so the risk of complications from injection is not high. However, discomfort or swelling may occasionally occur.
The effects and costs of hyaluronic acid injections vary depending on the area treated. For more details, please visit the following page.
What Are Hyaluronic Acid Injections? 9 Treatment Areas and Expected Aesthetic Benefits
8. Thread Lift
A thread lift is a treatment in which threads are inserted under the skin to lift and tighten it. By tightening the skin, wrinkles may become less noticeable.
Because a thread lift is similar to a surgical procedure, the physical burden is relatively greater and the downtime is longer compared to other treatments.
On the other hand, it offers the advantage of longer-lasting results. It may be a suitable option for those who feel: “I’m not comfortable with a surgical incision, but I’d like a treatment with a more significant effect.”
Treatment costs tend to be higher compared to other options, typically ranging from approximately ¥200,000 to ¥500,000.
For more information about thread lifts, please visit the following page.
What Is Non-Surgical Sagging and Lifting Treatment? An Introduction to Medical HIFU
For Wrinkle Treatment, Visit IC Clinic Shinjuku
Since the effects of skincare on wrinkles are limited, if you are looking to achieve smoother skin more effectively, you may want to consider visiting a clinic. Please keep this option in mind.
Our clinic can propose a treatment approach tailored to each patient’s wrinkle concerns from among 8 available procedures.
- Dermapen Microneedling
- ICON
- Agnes
- Fractional Laser
- HIFU
- Botulinum Toxin Injections
- Hyaluronic Acid Injections
- Thread Lift
If you have been struggling to improve your wrinkles through self-care alone, please feel free to come in for a consultation.
